BD-1047

• Description :

  BD-1047 is a selective functional antagonist of sigma receptors. BD-1047 attenuates Apomorphine (HY-12723) -induced climbing and Phencyclidine-induced head twitches[1].

• UNSPSC :

  12352101

• Target :

  Sigma Receptor

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  CN(C)CCN(CCC1=CC=C(Cl)C(Cl)=C1)C

• Molecular Formula :

  C13H20Cl2N2

• Molecular Weight :

  275.22

• References & Citations :

  [1]Skuza G, et al. Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity. Pharmacol Rep. 2006 Sep-Oct;58 (5) :626-35.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Citation 01 :

  Life Sci. 2020 Sep 15;257:118047.|Mol Neurobiol. 2025 Jun 1.|Behav Brain Res. 2025 Apr 27:484:115493.|Cell Rep. 2023 Jan 31;42 (1) :112011.|Eur J Med Res. 2025 Oct 30;30 (1) :1041.|Eur J Pharmacol. 2023 May 5:946:175647.|Int Immunopharmacol. 2023 Apr:117:109907.|Int Immunopharmacol. 2024 Jan 25:127:111382.|Int J Gen Med. 2025 Apr 4:18:1917-1931.|Mol Med. 2022 Aug 3;28 (1) :87.|Neural Regen Res. 2024 Apr 3.

• CAS Number :

  [138356-20-4]