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Autophagy inducer 7

CAT: 0804-HY-171047-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-171047-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Autophagy inducer 7 (Compound SSA) is an Autophagy and Apoptosis inducer. Autophagy inducer 7 activates autophagy by inhibiting Akt/mTOR signaling and the expression of downstream proteins. Autophagy inducer 7 suppresses DNA synthesis and causes a G0-G1 cell-cycle arrest. Autophagy inducer 7 inhibits tumor cell growth[1].
CAS Number
944159-20-0
UNSPSC
12352005
Target
Akt; Apoptosis; Autophagy; DNA/RNA Synthesis; mTOR
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.45
Smiles
CN(C)CCNC(CC1=C(C)/C(C2=CC=C(F)C=C21)=C/C3=CC=C(C=C3)SC)=O
Molecular Formula
C24H27FN2OS
Molecular Weight
410.55
References & Citations
[1]1. Gurpinar E, et al. A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy. Mol Cancer Ther. 2013 May;12 (5) :663-74.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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