Autophagy inducer 7

• Description:

  Autophagy inducer 7 (Compound SSA) is an Autophagy and Apoptosis inducer. Autophagy inducer 7 activates autophagy by inhibiting Akt/mTOR signaling and the expression of downstream proteins. Autophagy inducer 7 suppresses DNA synthesis and causes a G0-G1 cell-cycle arrest. Autophagy inducer 7 inhibits tumor cell growth[1].

• UNSPSC:

  12352005

• Target:

  Akt; Apoptosis; Autophagy; DNA/RNA Synthesis; mTOR

• Related Pathways:

  Apoptosis; Autophagy; Cell Cycle/DNA Damage; PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Purity:

  99.45

• Smiles:

  CN(C)CCNC(CC1=C(C)/C(C2=CC=C(F)C=C21)=C/C3=CC=C(C=C3)SC)=O

• Molecular Formula:

  C24H27FN2OS

• Molecular Weight:

  410.55

• References & Citations:

  [1]1. Gurpinar E, et al. A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy. Mol Cancer Ther. 2013 May;12 (5) :663-74.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [944159-20-0]