Autophagy-IN-C1

• UNSPSC Description:

  Autophagy-IN-C1 not only induces apoptosis but also blocks autophagy in hepatocellular carcinoma (HCC) cells.

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/autophagy-in-c1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N[C@H]([C@@]2([H])[N@](CC3C=C)CC[C@H]3C2)C4=C(C=C(OC)C=C5)C5=NC=C4

• Molecular Weight:

  578.55

• References & Citations:

  [1]Jin PR, et al. Cinchona Alkaloid-Inspired Urea-Containing Autophagy Inhibitor Shows Single-Agent Anticancer Efficacy. J Med Chem. 2021 Oct 14;64(19):14513-14525.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1494665-31-4