Autophagy-IN-6

• UNSPSC Description:

  Autophagy-IN-6 (compound 1u) is a lysosomotropic autophagy inhibitor and can induces LC3-II protein accumulation. Autophagy-IN-6 shows anti-proliferative activity[1].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/autophagy-in-6.html

• Smiles:

  O=C(NCCCCCC)C[C@@H](C1)[C@H]([C@@H](OC(C(C)C)=O)C2)[C@H](C3)[N@@]1[C@@H]2CN3CC4=CC=CC=C4

• Molecular Weight:

  469.66

• References & Citations:

  [1]Miura K, et al. Discovery of sp3-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors. Eur J Med Chem. 2024 Oct 5;280:116923.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported