Autophagy inducer 4

CAT: 0804-HY-146087-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-146087-01Size:5 mg
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Description
Autophagy inducer 4 is a Magnolol-based Mannich base derivatives, which can be used as an anticancer agent. Autophagy inducer 4 suppresses cancer cells via inducing autophagy. Autophagy inducer 4 has 76-fold improvement in cytotoxicity against T47D cells compared with Magnolol. Autophagy inducer 4 also possesses suppressive effects on migration of T47D and Hela cancer cells[1].
CAS Number
[2486455-03-0]
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-inducer-4.html
Purity
99.63
Solubility
10 mM in DMSO
Smiles
OC1=C(C2=CC(CC=C)=CC(C(N3CCOCC3)C4=CC(OC)=C(C(OC)=C4)OC)=C2O)C=C(CC=C)C=C1
Molecular Formula
C32H37NO6
Molecular Weight
531.64
References & Citations
[1]Xu T, et al. Semisynthesis of novel magnolol-based Mannich base derivatives that suppress cancer cells via inducing autophagy. Eur J Med Chem. 2020;205:112663.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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