Autophagy inducer 4
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Autophagy inducer 4
UNSPSC Description:
Autophagy inducer 4 is a Magnolol-based Mannich base derivatives, which can be used as an anticancer agent. Autophagy inducer 4 suppresses cancer cells via inducing autophagy. Autophagy inducer 4 has 76-fold improvement in cytotoxicity against T47D cells compared with Magnolol. Autophagy inducer 4 also possesses suppressive effects on migration of T47D and Hela cancer cells[1].Target Antigen:
AutophagyType:
Reference compoundRelated Pathways:
AutophagyApplications:
Cancer-programmed cell deathField of Research:
CancerAssay Protocol:
https://www.medchemexpress.com/autophagy-inducer-4.htmlSolubility:
10 mM in DMSOSmiles:
OC1=C(C2=CC(CC=C)=CC(C(N3CCOCC3)C4=CC(OC)=C(C(OC)=C4)OC)=C2O)C=C(CC=C)C=C1Molecular Weight:
531.64References & Citations:
[1]Xu T, et al. Semisynthesis of novel magnolol-based Mannich base derivatives that suppress cancer cells via inducing autophagy. Eur J Med Chem. 2020;205:112663.Shipping Conditions:
Room temperatureClinical Information:
No Development ReportedCAS Number:
2486455-03-0
