PRMT5-IN-49

• Description:

  PRMT5-IN-49 (Compound 4b16) is an inhibitor of PRMT5[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Related Pathways:

  Epigenetics

• Field of Research:

  Cancer

• Smiles:

  O=C(CCN1CC2=C(CC1)C=CC=C2)NC3=CC=C(C=C3)OC

• Molecular Formula:

  C19H22N2O2

• Molecular Weight:

  310.39

• References & Citations:

  [1]Zhu K, et al. Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3693-3699.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PRMT5

• CAS Number:

  [428853-17-2]