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(E/Z) -HOIPIN-1

CAT: 0804-HY-122881A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122881A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -HOIPIN-1 ((E/Z) -JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 value >2.8 μM. HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.
CAS Number
2470242-33-0
Product Name Alternative
(E/Z) -JTP-0819958
UNSPSC
12352005
Target
IKK
Related Pathways
NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
O=C(O[Na])C1=C(/C=C/C(C2=C(OC)C=CC=C2)=O)C=CC=C1
Molecular Formula
C17H13NaO4
Molecular Weight
304.27
References & Citations
[1]Katsuya K, et al. Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling. Biochem Biophys Res Commun. 2019 Feb 12;509 (3) :700-706.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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