(E/Z) -BML264

CAT: 0804-HY-118628-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-118628-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
(E/Z) -BML264 (N- (p-amylcinnamoyl) Anthranilic Acid) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker[1][2]. (E/Z) -BML264 (N- (p-amylcinnamoyl) Anthranilic Acid) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia[3].
CAS Number
[110683-10-8]
Product Name Alternative
N- (p-Amylcinnamoyl) anthranilic acid; ACA
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phospholipase; TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/e-z-bml264.html
Purity
99.63
Solubility
DMSO : 233.33 mg/mL (ultrasonic)
Smiles
CCCCCC1=CC=C(C=C1)/C=C/C(NC2=CC=CC=C2C(O)=O)=O
Molecular Formula
C21H23NO3
Molecular Weight
337.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Kraft R, et al. Inhibition of TRPM2 cation channels by N- (p-amylcinnamoyl) anthranilic acid. Br J Pharmacol. 2006 Jun;148 (3) :264-73.|[2]Harteneck C, et al. N- (p-amylcinnamoyl) anthranilic acid (ACA) : a phospholipase A (2) inhibitor and TRP channel blocker. Cardiovasc Drug Rev. 2007 Spring;25 (1) :61-75.|[3]Gwanyanya A, et al. Inhibition of the calcium-activated chloride current in cardiac ventricular myocytes by N- (p-amylcinnamoyl) anthranilic acid (ACA) . Biochem Biophys Res Commun. 2010 Nov 19;402 (3) :531-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-118628A-01BML264
HY-137451A-01(E/Z) -Sivopixant
HY-13779-01(E/Z) -J147
HY-145915A-01(E/Z) -ZINC09659342
HY-N1214A(E/Z) -Squalene
HY-10261B-01(E/Z) -Afatinib
HY-101284A-01(E/Z) -DMU2105
HY-123960B-01(E/Z) -Raphin1
HY-112149A-01(E/Z) -ZL0420
HY-W230975(E/Z) -Piperine

Alternative Products

CatalogName
C02155(E/Z) -BML264
MF-0148353-01BML264
A11962-100(E/Z) -Zotiraciclib ((E/Z) -TG-02, (E/Z) -SB1317) 100mg
A11962-2(E/Z) -Zotiraciclib ((E/Z) -TG-02, (E/Z) -SB1317) 2mg
A11962-1(E/Z) -Zotiraciclib ((E/Z) -TG-02, (E/Z) -SB1317) 1mg
A11962-50(E/Z) -Zotiraciclib ((E/Z) -TG-02, (E/Z) -SB1317) 50mg
A10141-1000(E/Z) -BIBW2992 (E/Z-Afatinib) 1g
A10141-200(E/Z) -BIBW2992 (E/Z-Afatinib) 200mg
A10141-500(E/Z) -BIBW2992 (E/Z-Afatinib) 500mg
A11962-10mM-D(E/Z) -Zotiraciclib ((E/Z) -TG-02, (E/Z) -SB1317) 10mM * 1mL in DMSO

Popular Products