(E/Z) -TG003

CAT: 0804-HY-15338A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15338A-01Size:5 mg
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Description
(E/Z) -TG003 is a racemic compound of (Z) -TG003 and (E) -TG003. (Z) -TG003 is a potent inhibitor of Clk1/Sty; inhibits Clk1 and Clk4 with IC50 values of 20 and 15 nM, respectively[1].
CAS Number
[300801-52-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-tg003.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1N/2CC)=CC=C1SC2=C\C(C)=O
Molecular Formula
C13H15NO2S
Molecular Weight
249.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Muraki M, et al. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem. 2004 Jun 4;279 (23) :24246-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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