(E/Z) -Rivanicline

• Description:

  (E/Z) -Rivanicline ((E/Z) -RJR-2403, (E/Z) -Metanicotine) is the E/Z mixture of Rivanicline (HY-13225A) . Rivanicline is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype, Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor[1].

• Product Name Alternative:

  (E/Z) -RJR-2403; (E/Z) -Metanicotine

• UNSPSC:

  12352005

• Target:

  NAChR

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Smiles:

  CNCC/C=C/C1=CC=CN=C1

• Molecular Formula:

  C10H14N2

• Molecular Weight:

  162.23

• References & Citations:

  [1]Luanratana O, et al. Alkaloids of Duboisia hopwoodii[J]. Phytochemistry, 1982, 21 (2) : 449-451.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [538-79-4]