(E/Z) -Rivanicline

• Description :

  (E/Z) -Rivanicline ((E/Z) -RJR-2403, (E/Z) -Metanicotine) is the E/Z mixture of Rivanicline (HY-13225A) . Rivanicline is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype, Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor[1].

• Product Name Alternative :

  (E/Z) -RJR-2403; (E/Z) -Metanicotine

• UNSPSC :

  12352005

• Target :

  NAChR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  CNCC/C=C/C1=CC=CN=C1

• Molecular Formula :

  C10H14N2

• Molecular Weight :

  162.23

• References & Citations :

  [1]Luanratana O, et al. Alkaloids of Duboisia hopwoodii[J]. Phytochemistry, 1982, 21 (2) : 449-451.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [538-79-4]