(E/Z) -Raphin1

CAT: 0804-HY-123960B-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-123960B-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -Raphin1 is an inhibitor of PPP1R15B, a regulatory subunit of protein phosphatase 1. (E/Z) -Raphin1 is orally available and can cross the blood-brain barrier. (E/Z) -Raphin1 can be used in neurological research[1].
CAS Number
[94023-67-3]
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332-H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-z-raphin1.html
Smiles
ClC1=C(Cl)C(/C=N/NC(N)=N)=CC=C1
Molecular Formula
C8H8Cl2N4
Molecular Weight
231.08
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Krzyzosiak A, et al. Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B. Cell. 2018 Aug 23;174 (5) :1216-1228.e19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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