BMS-269223

• Description:

  BMS-269223 is a potent, selective and orally active factor Xa inhibitor (Ki = 6.5 nM, EC2xPT = 32 μM) . BMS-269223 can prolong prothrombin time and inhibit thrombosis formation. BMS-269223 can be used for the research of cardiovascular disease[1].

• UNSPSC:

  12352005

• Target:

  Factor Xa

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Smiles:

  CC(O1)=CC2=C1C=CC(N/C(N[C@H]3CCCCN(CC(N4CCCC4)=O)C3=O)=N/C#N)=C2

• Molecular Formula:

  C23H28N6O3

• Molecular Weight:

  436.51

• References & Citations:

  [1]Shi Y, et al. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19 (15) :4034-41.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [288077-60-1]