BMS-753426

• UNSPSC Description:

  BMS-753426 is a potent and orally bioavailable antagonist of CCR2.

• Target Antigen:

  CCR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bms-753426.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N[C@H]1[C@@H](N2C([C@@H](NC3=C4C=C(C(F)(F)F)C=CC4=NC=N3)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O

• Molecular Weight:

  506.56

• References & Citations:

  [1]Yang MG, et al. Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2. ACS Med Chem Lett. 2021 May 25;12(6):969-975.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1004536-52-0