BMS-753426

• Description :

  BMS-753426 is a potent and orally bioavailable antagonist of CCR2.

• UNSPSC :

  12352005

• Target :

  CCR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bms-753426.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(N[C@H]1[C@@H](N2C([C@@H](NC3=C4C=C(C(F)(F)F)C=CC4=NC=N3)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O

• Molecular Formula :

  C25H33F3N6O2

• Molecular Weight :

  506.56

• References & Citations :

  [1]Yang MG, et al. Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2. ACS Med Chem Lett. 2021 May 25;12 (6) :969-975.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CCR2

• CAS Number :

  [1004536-52-0]