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BMS-753426

CAT: 0804-HY-115874Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115874Size:1 Each
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Description
BMS-753426 is a potent and orally bioavailable antagonist of CCR2.
CAS Number
1004536-52-0
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bms-753426.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@H]1[C@@H](N2C([C@@H](NC3=C4C=C(C(F)(F)F)C=CC4=NC=N3)CC2)=O)CC[C@@H](NC(C)(C)C)C1)=O
Molecular Formula
C25H33F3N6O2
Molecular Weight
506.56
References & Citations
[1]Yang MG, et al. Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2. ACS Med Chem Lett. 2021 May 25;12 (6) :969-975.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR2

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