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BMS-764459

CAT: 0804-HY-14225Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-14225Size:1 Each
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Description
BMS-764459 is a CRF1 antagonist. BMS-764459 can be used for the research of neurological disorders such as depression and anxiety. BMS-764459 is also an atypical CYP1A1 inducer[1][2].
CAS Number
[1188407-45-5]
UNSPSC
12352005
Target
CRFR; Cytochrome P450
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-764459.html
Solubility
10 mM in DMSO
Smiles
N#CC(N=C1NC2=CC(C)=C(OC(F)F)N=C2C)=CN([C@@H](C3CC3)COC)C1=O
Molecular Formula
C19H21F2N5O3
Molecular Weight
405.40
References & Citations
[1]David K. Leahy, et al. Development of an Efficient Synthesis of Two CRF Antagonists for the Treatment of Neurological Disorders. Org. Process Res. Dev. 2010, 14, 5, 1221-1228.|[2]Simic D, et al. MicroRNA changes associated with atypical CYP1A1 inducer BMS-764459. Toxicology. 2013 Sep 15;311 (3) :169-77.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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