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BMS-509744

CAT: 0804-HY-11092-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-11092-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM.
CAS Number
439575-02-7
UNSPSC
12352005
Target
Itk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/BMS-509744.html
Concentration
10mM
Purity
98.09
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
CC(C(C)(C)C)NCC1=CC=C(C(NC2=NC=C(SC3=CC(C(N4CCN(C(C)=O)CC4)=O)=C(OC)C=C3C)S2)=O)C=C1
Molecular Formula
C32H41N5O4S2
Molecular Weight
623.83
References & Citations
[1]Lin TA, et al. Selective Itk inhibitors block T-cell activation and murine lung inflammation. Biochemistry.?2004 Aug 31;43 (34) :11056-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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