BMS-509744

• UNSPSC Description:

  BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM.

• Target Antigen:

  Itk

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/BMS-509744.html

• Purity:

  98.09

• Solubility:

  DMSO : 21.9 mg/mL (ultrasonic;warming)

• Smiles:

  CC(C(C)(C)C)NCC1=CC=C(C(NC2=NC=C(SC3=CC(C(N4CCN(C(C)=O)CC4)=O)=C(OC)C=C3C)S2)=O)C=C1

• Molecular Weight:

  623.83

• References & Citations:

  [1]Lin TA, et al. Selective Itk inhibitors block T-cell activation and murine lung inflammation. Biochemistry.?2004 Aug 31;43(34):11056-62.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  439575-02-7