MK-0963

• Description :

  MK-0963 is a steroidal 5α-reductase inhibitor. MK-0963 reduces serum dihydrotestosterone (DHT) concentrations in a dose-dependent manner. MK-0963 can be used for the study of dihydrotestosterone-related diseases such as benign prostate hyperplasia (BPH) [1].

• CAS Number :

  [103497-68-3]

• Product Name Alternative :

  L 654066

• UNSPSC :

  12352005

• Target :

  5 alpha Reductase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Smiles :

  C[C@@]12[C@](CC[C@@H]2C(CC(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](NC(C=C4)=O)([H])CC3)C)([H])CC1

• Molecular Formula :

  C23H35NO2

• Molecular Weight :

  357.53

• References & Citations :

  [1]Depré M, et al. Pharmacodynamics and tolerability of L-654,066, a steroid 5 alpha-reductase inhibitor, in men. Clin Pharmacol Ther. 1992 Oct;52 (4) :409-12.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1