PSB-0963

• Target:

  CD73

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  PSB-0963 is a selective competitive extracellular 5'-nucleotidase (eN/CD73) inhibitor with a Ki value of 150 nM for rat extracellular 5'-nucleotidase. It exhibits greater selectivity compared to other extracellular nucleotidases (NTPDases 1-3) and P2Y receptors. PSB-0963 is applicable in cancer research.

• Smiles:

  O=C1C2=C(C(C3=C(NC4=CC5=CC6=C(C=CC=C6)C=C5C=C4)C=C(S(=O)([O-])=O)C(N)=C13)=O)C=CC=C2.[Na+]

• Molecular Formula:

  C28H17N2NaO5S

• Molecular Weight:

  516.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1213268-73-5