PSB-0963

• Description:

  PSB-0963 is a selective and competitive ecto-5'-nucleotidase (eN/CD73) inhibitor with a Ki of 150 nM for rat ecto-5'-nucleotidase. PSB-0963 shows high selectivity over other ectonucleotidases (NTPDases 1-3) and P2Y receptors. PSB-0963 can be used for the study of cancer[1].

• UNSPSC:

  12352005

• Target:

  CD73

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Smiles:

  O=C1C2=C(C(C3=C(NC4=CC5=CC6=C(C=CC=C6)C=C5C=C4)C=C(S(=O)(O[Na])=O)C(N)=C13)=O)C=CC=C2

• Molecular Formula:

  C28H17N2NaO5S

• Molecular Weight:

  516.50

• References & Citations:

  [1]Baqi Y, et al. Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem. 2010;53 (5) :2076-2086.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1213268-73-5]