MK-8527

MK-8527

• CAS Number: 1810869-23-8
• UNSPSC Description: MK-8527 is an HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI). MK-8527 has a similar inhibitory mechanism to ISL (HY-104012)[1].
• Target Antigen: HIV; Reverse Transcriptase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/mk-8527.html
• Solubility: DMSO : 116.67 mg/mL (ultrasonic)
• Smiles: OC[C@]1(C#C)[C@@H](O)C[C@H](N2C3=NC(Cl)=NC(N)=C3C=C2)O1
• Molecular Weight: 308.72
• References & Citations: [1]Gillespie SW, et al. Islatravir: evaluation of clinical development for HIV and HBV. Expert Opin Investig Drugs. 2024 Feb;33(2):85-93.
• Shipping Conditions: Blue Ice
• Clinical Information: Phase 2