MK-0773

• Description :

  MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM.

• Product Name Alternative :

  PF-05314882

• UNSPSC :

  12352005

• Target :

  Androgen Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/MK-0773.html

• Concentration :

  10mM

• Purity :

  99.92

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic)

• Smiles :

  O=C([C@H]1CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)C=C(F)C(N(C)[C@]4([H])CC[C@]32[H])=O)NCC5=NC6=CC=CN=C6N5

• Molecular Formula :

  C27H34FN5O2

• Molecular Weight :

  479.59

• References & Citations :

  [1]Schmidt A, et al. Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology. J Biol Chem. 2010 May 28;285

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [606101-58-0]