NMS-0963

CAT: 0931-MF-0121052-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0121052-01Size:10 mg
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CAS Number
2765304-82-1
Target
Syk
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
NMS-0963 (compound 1), an orally active inhibitor of spleen tyrosine kinase (SYK), demonstrates an IC50 value of 3 nM. Additionally, NMS-0963 effectively inhibits the proliferation of the BaF3-TEL/SYK cell line at 27 nM [1].
Smiles
C(N[C@H](CN1CCC1)C)(=O)C2=CC(=NN2C)C3=NC(NC4=CC(OC)=CC(OC)=C4)=NC=C3
Molecular Formula
C23H29N7O3
Molecular Weight
451.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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