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VDX-111

CAT: 0931-T87611-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87611-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
158983-23-4
Target
Necroptosis|||RIP kinase
Related Pathways
Apoptosis|||NF-?B
Bioactivity
VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].
Smiles
C[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]
Molecular Formula
C29H45BrO4
Molecular Weight
537.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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