VDX-111

CAT: 0931-T87611-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T87611-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

158983-23-4

Target

Necroptosis, RIP kinase

Related Pathways

Apoptosis, NF-κB

Bioactivity

VDX-111, an analog of vitamin D, exhibits cytotoxicity in ovarian cancer cells by upregulating the RIPK1/RIPK3 pathway and inducing necroptosis. It also promotes the expression of cytokines and demonstrates antitumor activity in a mouse model [1].

Smiles

C[C@@]12[C@](\C(=C\C=C/3\C[C@@H](OC(CBr)=O)C[C@H](O)C3=C)\CCC1)(CC[C@@]2([C@@H](CCCC(C)(C)O)C)[H])[H]

Molecular Formula

C29H45BrO4

Molecular Weight

537.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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