CHS-111

CAT: 0931-T27013-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T27013-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

886755-63-1

Target

Reactive Oxygen Species, Others

Related Pathways

Others, NF-κB, Immunology/Inflammation, Metabolism

Bioactivity

CHS-111 is a benzyl indazole compound that inhibits superoxide anion (O (2) (-) ) generation and reduces fMLP-stimulated PLD activity (IC (50) 3.9±1.2μM) . It inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homology (Rho) A, and reduces the membrane recruitment of RhoA in fMLP-stimulated cells.

Smiles

C(N1C(=C2C(=N1)C=CC=C2)C3=CC=C(CO)C=C3)C4=CC=CC=C4

Molecular Formula

C21H18N2O

Molecular Weight

314.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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CHS-111

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