GXF-111

CAT: 0931-T79034-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79034-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Epigenetic Reader Domain, PROTACs

Related Pathways

Chromatin/Epigenetic, PROTAC

Bioactivity

GXF-111, a proteolysis targeting chimera (PROTAC) molecule, efficiently induces the selective degradation of the BRD3 and BRD4-L proteins. It exhibits high binding affinities to both BRD3 BD1 and BRD3 BD2, with K i values of 11.97 nM and 2.35 nM, respectively. This compound is utilized in cancer research [1].

Molecular Formula

C42H42ClN7O3

Molecular Weight

728.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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