SKA-111

• Description :

  SKA-111 is a selective calcium-activated potassium phannel (potassium phannel) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

• CAS Number :

  1369170-24-0

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  214.29

• Molecular Formula :

  C12H10N2S

• Notes :

  Research use only, not for human use.

• Receptor :

  Potassium Channel