SKA-111

• Description:

  SKA-111 is a selective calcium-activated potassium phannel (potassium phannel) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  214.29

• Molecular Formula:

  C12H10N2S

• Notes:

  Research use only, not for human use.

• Receptor:

  Potassium Channel

• CAS Number:

  1369170-24-0