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ARGX-111

CAT: 0931-T9901A-1879-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T9901A-1879-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
ARGX-111 is a defucosylated anti-MET antibody that inhibits both HGF-dependent and HGF-independent signaling and reduces MET expression on tumor cell surfaces. It suppresses tumor metastasis by enhancing antibody-dependent cellular cytotoxicity (ADCC) to deplete MET-expressing circulating tumor cells. In metastatic breast cancer orthotopic mouse models, ARGX-111 has been shown to deplete circulating tumor cells and inhibit bone and lung metastases. This compound is suitable for research in cancers such as breast cancer.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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HY-P991660ARGX-111
HY196066-01Research Grade Anti-Human MET/c-Met/HGFR (ARGX-111)
A135976Anti-MET/c-Met/HGFR (ARGX-111) Biosimilar (Monoclonal, IgG)
HY-P991066-01ARGX-119
047748Complement C2 (ARGX-117) discontinued
048306IL-22Ra (ARGX-112) discontinued
C00477-01Anti-Complement C2 (ARGX-117)
F1234-.1Anti-IL-22Ra Antibody (ARGX-112)
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