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ARGX-111

CAT: 0931-T9901A-1879-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1879-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
ARGX-111 is a defucosylated anti-MET antibody that inhibits both HGF-dependent and HGF-independent signaling and reduces MET expression on tumor cell surfaces. It suppresses tumor metastasis by enhancing antibody-dependent cellular cytotoxicity (ADCC) to deplete MET-expressing circulating tumor cells. In metastatic breast cancer orthotopic mouse models, ARGX-111 has been shown to deplete circulating tumor cells and inhibit bone and lung metastases. This compound is suitable for research in cancers such as breast cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-P991660ARGX-111
PTX25718Anti-Human MET/c-Met/HGFR (ARGX-111)
HY196066-01Research Grade Anti-Human MET/c-Met/HGFR (ARGX-111)
A135976Anti-MET/c-Met/HGFR (ARGX-111) Biosimilar (Monoclonal, IgG)
GTR18016442Argx Antibody
HY-P991066-01ARGX-119
GTR18679082-01ARGX-119 Antibody
A2701-1mg*5Anti-Complement C2 (ARGX-117)
047748Complement C2 (ARGX-117) discontinued
048306IL-22Ra (ARGX-112) discontinued

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