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RIPK1-IN-19

CAT: 0931-T87334-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T87334-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2763831-43-0
Target
RIP kinase
Related Pathways
NF-κB, Apoptosis
Purity
0.9881
Bioactivity
RIPK1-IN-19 is a selective and potent bimodal RIPK1 inhibitor with IC50=15 nM that protects against cell necrosis and works well in the tnf α-induced Systemic Inflammatory Response Syndrome (SIRS) model and imiquimod (IMQ) -induced psoriasis model.
Smiles
C(N[C@@H](C)C1=CC(F)=CC=C1)(=O)C=2C=3C(N(C)C2)=CC=C(C3)C4=CC=5N(C=C4)N=C(NC(=O)C6CC6)N5
Molecular Formula
C28H25FN6O2
Molecular Weight
496.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C