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PLK1/BRD4-IN-1

CAT: 0013-GTR19185523-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185523-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLK1/BRD4-IN-1 (9b) is a potent, orally bioavailable dual inhibitor targeting PLK1 and BRD4 with IC50 values of 22 nM and 109 nM, respectively. It demonstrates significant anti-tumor activity in vivo, making it a valuable chemical probe for oncology research, particularly in studying cell cycle progression and epigenetic regulation in cancer models.
CAS Number
2412707-81-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research
Smiles
C (N1C=2C (N3C ([C@H]1CC) =NN=C3C) =CN=C (NC4=C (OC) C=C (C (NC5CCN (C) CC5) =O) C=C4) N2) C6CCCCC6
Molecular Formula
C31H43N9O2
Molecular Weight
573.73
Storage Conditions
-20°C
Notes
For research use only.

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