NNRT-IN-10

• Target :

  HIV Protease|||Cytochromes P450|||Potassium Channel|||Reverse Transcriptase

• Related Pathways :

  Metabolism|||Proteases/Proteasome|||Microbiology/Virology|||Membrane transporter/Ion channel

• Bioactivity :

  NNRT-IN-10 is a potent, selective, and orally bioavailable non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1. The compound exhibits EC50 values ranging from 1.16 to 18.3 nM against HIV and its variants. NNRT-IN-10 has favorable pharmacokinetic properties and safety profile, making it suitable for research on AIDS caused by HIV-1.

• Smiles :

  O(C=1C2=C(N=C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)N1)N=CC=C2)C5=C(C)C=C(/C=C/C#N)C=C5C

• Molecular Formula :

  C31H32N6O3S

• Molecular Weight :

  568.69

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2459751-62-1