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NNRT-IN-10

CAT: 0931-T210761-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T210761-01Size: 10 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2459751-62-1
Target
HIV Protease|||Cytochromes P450|||Potassium Channel|||Reverse Transcriptase
Related Pathways
Metabolism|||Proteases/Proteasome|||Microbiology/Virology|||Membrane transporter/Ion channel
Bioactivity
NNRT-IN-10 is a potent, selective, and orally bioavailable non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1. The compound exhibits EC50 values ranging from 1.16 to 18.3 nM against HIV and its variants. NNRT-IN-10 has favorable pharmacokinetic properties and safety profile, making it suitable for research on AIDS caused by HIV-1.
Smiles
O(C=1C2=C(N=C(NC3CCN(CC4=CC=C(S(C)(=O)=O)C=C4)CC3)N1)N=CC=C2)C5=C(C)C=C(/C=C/C#N)C=C5C
Molecular Formula
C31H32N6O3S
Molecular Weight
568.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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