EGFR/CDK2-IN-2

CAT: 0931-T79727-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79727-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

EGFR, CDK

Related Pathways

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, JAK/STAT signaling, Angiogenesis

Bioactivity

EGFR/CDK2-IN-2 (compound 6a) is a dual inhibitor targeting EGFR and CDK-2, with IC50 values of 19.6 nM and 87.9 nM, respectively. It induces apoptosis in MCF-7 cells and arrests cell cycle progression in the S phase, demonstrating notable anticancer activity with an IC50 of 0.39 μM [1].

Molecular Formula

C49H32N12O2S2

Molecular Weight

884.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5821388	EGFR/CDK2-IN-2
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GTR19212935-01	EGFR/CDK2-IN-1
GTR19274616-01	EGFR/CDK2-IN-5
HY-176124	CDK2 ligand-2
HY-163815-01	CDK2 degrader 2
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EGFR/CDK2-IN-2

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