EGFR/CDK2-IN-5

CAT: 0013-GTR19274616-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274616-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR/CDK2-IN-5 is a potent dual inhibitor of EGFR and CDK2, with IC50 values of 17.30 nM and 212.10 nM, respectively. It can also inhibit EGFRT790M with an IC50 of 123.8 nM and demonstrates significant anticancer activity. This compound induces cell cycle arrest in the G1 and S phases and promotes apoptosis (apoptosis), characterized by increased levels of caspase-3/9 and Bax and decreased levels of Bcl-2. EGFR/CDK2-IN-5 is applicable in research related to lung cancer, breast cancer, and leukemia.

Storage Conditions

-20°C

Notes

For research use only.

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EGFR/CDK2-IN-5

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