Products for Research Use Only
RegisterLogin

EGFR/CDK2-IN-1

CAT: 0013-GTR19212935-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19212935-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EGFR/CDK2-IN-1 is a dual inhibitor of EGFR and CDK2, exhibiting cytotoxic effects on MCF7 and HepG2 cell lines in vitro. This activity supports its utility as a research tool for investigating oncology pathways and evaluating potential therapeutic strategies in cancer cell biology.
CAS Number
2841405-96-5
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin; Cell Biology, Signal Transduction
Smiles
ClC1=C (C=2OC (/C=C/C (=O) C3=CC=C (Br) C=C3) =CC2) C=CC=C1
Molecular Formula
C19H12BrClO2
Molecular Weight
387.65
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Egfr/cdk2-IN-1
CAS Number2841405-96-5
PubChem CID6199344
IUPAC Name(E)-1-(4-bromophenyl)-3-[5-(2-chlorophenyl)furan-2-yl]prop-2-en-1-one
Molecular FormulaC19H12BrClO2
Molecular Weight387.7
XLogP5.8
Topological Polar Surface Area30.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity431
SMILES
C1=CC=C(C(=C1)C2=CC=C(O2)/C=C/C(=O)C3=CC=C(C=C3)Br)Cl
InChI
InChI=1S/C19H12BrClO2/c20-14-7-5-13(6-8-14)18(22)11-9-15-10-12-19(23-15)16-3-1-2-4-17(16)21/h1-12H/b11-9+
InChIKey
YIOGDNXXYFSGJY-PKNBQFBNSA-N
Chemical Structure
2D Structure
2D structure of Egfr/cdk2-IN-1
CAS: 2841405-96-5
CID: 6199344
Formula: C19H12BrClO2
MW: 387.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight387.7
XLogP35.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass385.97092
Monoisotopic Mass385.97092
Topological Polar Surface Area30.2 Ų
Heavy Atom Count23
Formal Charge0
Complexity431
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19230316-01EGFR/CDK2-IN-2
GTR19230315-01EGFR/CDK2-IN-3
GTR19274616-01EGFR/CDK2-IN-5
GTR19230314-01EGFR/CDK2-IN-4
GTR17928193-01CDK1/CDK2/CDK3 Antibody
GTR17927656-01CDK1/CDK2/CDK3 Antibody
GTR17926668-01CDK1/CDK2/CDK3 Antibody
GTR18796257-01CDK2/CDK1 Antibody
GTR19185841-01EGFR/HER2/CDK9-IN-1
GTR19237748-01CDK2 degrader 1

Alternative Products

CatalogName
T72844-01EGFR/CDK2-IN-1
T79727-01EGFR/CDK2-IN-2
HY-156116EGFR/CDK2-IN-4
MBS5821389EGFR/CDK2-IN-3
sc-80543EGFR (EGFR.1)
HY-149436CDK2/Bcl2-IN-1
T209262-01CDK2/MDM2-IN-1
T204166-01CDK2/9-IN-1
T89458-01CDK2/4-IN-1
HY-173224CDK2/PIM1-IN-1

Popular Products