AMG-628, (R) -

CAT: 0931-T71736-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T71736-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

862269-93-0

Target

Others, TRP/TRPV Channel

Related Pathways

Others, Membrane transporter/Ion channel

Bioactivity

AMG-628, (R) - is the R isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.

Smiles

C[C@@H](N1CCN(CC1)C1=CC(OC2=C3N=C(NC(C)=O)SC3=CC=C2)=NC=N1)C1=CC=C(F)C=C1

Molecular Formula

C25H25FN6O2S

Molecular Weight

492.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T30565-01	BPH-628
T87041	NST-628
T24187-01	J 628
T69740-01	AMG-315
T68408-01	AMG-1
T23722-01	AMG-7980
T29968-01	AMG-0347

Alternative Products

Catalog	Name
GTR19195636-01	AMG-628
GTR19211448-01	AMG-628, (S) -
HY-123374	(Rac) -AMG 628
GTR19208819-01	AMG-628, (R) -
MBS5814243	AMG-628, (R)-
HY-169780	(S) -AMG-628
MBS5811084	AMG-628, (S)-
A8371-100	AZ 628
HY-118950	J 628
MBS5780198-01	BPH-628

AMG-628, (R) -

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