AMG-315

CAT: 0931-T69740-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T69740-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2244425-65-6

Target

Others

Related Pathways

Others

Bioactivity

AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R) -dimethylanandamide. AMG-315 is a high affinity ligand for the CB1 receptor (Ki of 7.8 ± 1.4 nM) that behaves as a potent CB1 agonist in vitro (EC50 = 0.6 ± 0.2 nM) . AMG-315 is the first potent AEA analogue with significant stability for all endocannabinoid hydrolyzing enzymes as well as the oxidative enzymes COX-2. AMG-315 will serve as a very useful endocannabinoid probe.

Smiles

C(CC/C=C\C/C=C\C/C=C\[C@H](/C=C\CCCCC)C)C(N[C@@H](CO)C)=O

Molecular Formula

C24H41NO2

Molecular Weight

375.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-178723	AMG-315
BA5733-50	AMG-009
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B5496-10	AMG 548
A1174-5.1	AMG-517
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AMG-315

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