NST-628

• CAS Number :

  3002056-30-3

• Target :

  Raf|||Molecular Glues|||MEK

• Related Pathways :

  PROTAC|||MAPK

• Purity :

  0.9862

• Bioactivity :

  NST-628 is a pan-RAF-MEK molecular glue that prevents RAF from phosphorylating and activating MEK, inhibiting the RAF-MEK signaling complex.

• Smiles :

  O=C1OC=2C=C(OC3=NC=CC=C3F)C=CC2C(=C1CC=4C=CN=C(NS(=O)(=O)NC)C4F)C

• Molecular Formula :

  C22H18F2N4O5S

• Molecular Weight :

  488.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C