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AMG-628, (S) -

CAT: 0013-GTR19211448-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19211448-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-628, the (S) -enantiomer, is a potent and selective ATP-competitive Raf kinase inhibitor. It also suppresses VEGFR2, Lyn, Flt1, and Fms activity and has demonstrated in vitro efficacy against B-RafV600E mutant colon and melanoma lines by inhibiting proliferation and inducing cell cycle arrest and apoptosis.
CAS Number
862269-92-9
Field of Research
Pharmacology & Drug Discovery
Smiles
O (C1=C2C (SC (NC (C) =O) =N2) =CC=C1) C=3C=C (N=CN3) N4CCN ([C@@H] (C) C5=CC=C (F) C=C5) CC4
Molecular Formula
C25H25FN6O2S
Molecular Weight
492.57
Storage Conditions
-20°C
Notes
For research use only.

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