AMG-1

• Target:

  Calcium Channel|||Others

• Related Pathways:

  Others|||Membrane transporter/Ion channel|||Metabolism

• Bioactivity:

  AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo.

• Smiles:

  ClC=1C(=CC(C(F)(F)F)=CC1)C=2C=NC(NC(=O)C3=C(F)C=CC=C3F)=CN2

• Molecular Formula:

  C18H9ClF5N3O

• Molecular Weight:

  413.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  903591-53-7