AMG-628

• Target :

  Others|||TRP/TRPV Channel

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations.

• Smiles :

  O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)N4CCN(C(C)C5=CC=C(F)C=C5)CC4

• Molecular Formula :

  C25H25FN6O2S

• Molecular Weight :

  492.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  862269-73-6