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Ciprostene (free base)

CAT: 0931-T68639-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T68639-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
81845-44-5
Target
Prostaglandin Receptor, Others
Related Pathways
GPCR/G Protein, Others, Immunology/Inflammation
Bioactivity
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2) . In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-induced platelet aggregation. Ciprostene was evaluated in clinical trials in patients with peripheral vascular disease. It was found to reduce restenosis in patients with coronary artery disease undergoing therapeutic percutaneous transluminal coronary angioplasty.
Smiles
C[C@@]12[C@@]([C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1)(C\C(=C\CCCC(O)=O)\C2)[H]
Molecular Formula
C22H36O4
Molecular Weight
364.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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