Dibrospidium Free Base

CAT: 0931-MF-0143340-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0143340-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
86641-78-3
Target
Others
Related Pathways
Others
Bioactivity
Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correlate with spirobromine antitumor activity. Spirobromin is superior to prospidin by the power of the anti-inflammatory effect. Spyrobromin can diminish the latent period of the development of tumours in the experimental rats at intraperitoneal administration. At intragastric administration of the drug no decrease was noted in the latent period and no increase of tumours was observed in the experimental groups of the animals as compared with control. Dibrospidium has been examined for the treatment of bone cancer. The oral route of administration is the most safe with respect to the oncogenic risk. It was noted that spirobromin exerted the most pronounced toxic action on erythrocytes. Dibrospidium is used for the treatment of acute leukemias (mainly in combinatio......
Smiles
C(CCBr)(=O)N1CC[N+]2(CC[N+]3(CC2)CCN(C(CCBr)=O)CC3)CC1
Molecular Formula
C18H32Br2N4O2
Molecular Weight
496.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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