Antitumor agent-163

CAT: 0931-T209878-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T209878-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Target

Carbonic Anhydrase

Related Pathways

Metabolism

Bioactivity

Antitumor agent-163 (Compound 3) serves as a photosensitizer in molecular-targeted photodynamic therapy (MT-PDT) aimed at carbonic anhydrase IX (CAIX) . Under illumination at 540 nm, Antitumor agent-163 inactivates CAIX protein through singlet oxygen generation without affecting internal standard proteins such as α-tubulin, β-actin, and proliferating cell nuclear antigen (PCNA) . It induces cell membrane damage and reduces cell viability with IC50 values of 0.2 μM for A549 and 0.05 μM for U87MG. Furthermore, Antitumor agent-163 demonstrates antitumor activity in mouse models.

Molecular Formula

C27H32BF2I2N5O4S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T10342-01	Antitumor agent-2
T211211-01	Antitumor agent-203
T209984-01	Antitumor agent-156
T209806-01	Antitumor agent-151
T209096-01	Antitumor agent-131
T206452-01	Antitumor agent-200
T205444-01	Antitumor agent-198
T200846-01	Antitumor agent-188
T89076-01	Antitumor agent-175
T88732-01	Antitumor agent-164

Alternative Products

Catalog	Name
HY-163691	Antitumor agent-163
M26058-01	Antitumor agent-19
HY-162128	Antitumor agent-130
HY-161425	Antitumor agent-149
HY-155034	Antitumor agent-102
HY-151292	Antitumor agent-74
HY-116447-01	Antitumor agent-159
HY-149717	Antitumor agent-122
HY-115948	Antitumor agent-46
HY-152537	Antitumor agent-84

Antitumor agent-163

Related Products

Alternative Products

Popular Products