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RTx-152

CAT: 0013-GTR19262384-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262384-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RTx-152 is an allosteric Polθ-pol inhibitor (IC50: 6.2 nM) that targets Polθ captured on DNA. It selectively kills cancer cells with homologous recombination (HR) defects and inhibits resistance to PARP inhibitors across various genetic backgrounds, including HR-proficient cells. Additionally, RTx-152 selectively eliminates BRCA2-deficient cells.
CAS Number
3035072-48-8
Field of Research
Cell Biology, Molecular Biology
Smiles
O=C (OC=1C (=CC (=CC1C (F) (F) F) C (F) (F) F) N2C (=O) N (C) CC2) N (C3=CC=C (F) C=C3) C
Molecular Formula
C20H16F7N3O3
Molecular Weight
479.35
Storage Conditions
-20°C
Notes
For research use only.

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