Apoptosis inducer 36

• Target:

  Apoptosis|||Pyroptosis

• Related Pathways:

  Immunology/Inflammation|||Apoptosis

• Bioactivity:

  Apoptosisinducer 36 (Compound 42) exhibits anti-leukemic activity by reducing leukemia stem cells (LSC) and inducing differentiation. It inhibits proliferation of AML cells by causing cell cycle arrest in the G1 phase, and induces PANoptosis, which includes apoptosis, pyroptosis, and necrosis.

• Smiles:

  C[C@@]12[C@] ([C@]3 ([C@@] (CC1) (OC (=O) C (=C) C3) [H]) [H]) (CC[C@@H]2O[Si] (C (C) C) (C (C) C) C (C) C) [H]

• Molecular Formula:

  C23H40O3Si

• Molecular Weight:

  392.647

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2831492-41-0