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PPARγ/δ modulator 2

CAT: 0931-T204395-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204395-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PPAR
Related Pathways
Metabolism, DNA Damage/DNA Repair
Bioactivity
PPARγ/δ modulator 2 (Compound 3h) functions as a PPARγ agonist and a PPARδ antagonist, with Ki values for PPARγ and PPARδ of 2.8 μM and 43 nM, respectively. It significantly enhances adiponectin production and promotes adipogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBM-MSCs) . This compound is applicable in research on metabolic diseases related to hypoadiponectinemia.
Smiles
C1[C@@H](C([C@@H]([Se]1)CN2C=NC3=C(N=C(N=C32)Cl)NCC4=CC(=CC=C4)I)O)O
Molecular Formula
C17H17ClIN5O2Se
Molecular Weight
564.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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