PDE4-IN-22

CAT: 0931-T201304-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T201304-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

TNF, Interleukin, PDE

Related Pathways

Metabolism, Apoptosis, Immunology/Inflammation

Bioactivity

PDE4-IN-22 (Compound 2e) is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 2.4 nM. It exhibits anti-inflammatory properties and demonstrates significant anti-psoriatic effects in an Imiquimod-induced psoriasis mouse model.

Smiles

[C@@H](NC(=O)C=1N(CC)N=CC1)(C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3CCN(C)CC3)NC(CC)=O)C)C=C2)=O)[C@]4(CC[C@H](C)CC4)[H]

Molecular Formula

C22H19F4N3O3

Molecular Weight

449.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T60934-01	PDE4-IN-9
T63912-01	PDE4-IN-12
T50023-01	PDE4-IN-20
T62969-01	PDE4-IN-6
T61295-01	PDE4-IN-5
T39210	PDE4-IN-4

Alternative Products

Catalog	Name
GTR19239835-01	PDE4-IN-22
BA8215-10	PDE4-IN-14
HY-169981	PDE4-IN-24
HY-162583	PDE4-IN-17
HY-132887	PDE4-IN-3
HY-151174	PDE4-IN-12
HY-161381	PDE4-IN-15
HY-115871	PDE4-IN-4
HY-179639	PDE4-IN-30
HY-W787896-01	PDE4-IN-25

PDE4-IN-22

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