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Apoptosis inducer 30

CAT: 0931-T201277-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T201277-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Caspase|||Reactive Oxygen Species|||Apoptosis|||Cytochromes P450
Related Pathways
Apoptosis|||NF-?B|||Metabolism|||Immunology/Inflammation|||Proteases/Proteasome
Bioactivity
Apoptosisinducer 30 (Compound 15a) acts as an anticancer agent. It induces apoptosis in MCF-7 cells through the mitochondrial pathway. This compound elevates intracellular levels of reactive oxygen species (ROS), decreases mitochondrial membrane potential, and arrests the cell cycle at the G0/G1 phase. Apoptosisinducer 30 inhibits cell growth, with an IC50 value of 0.32 ?M against MCF-7 cells, and suppresses tumor growth in a mouse breast cancer model.
Molecular Formula
C52H69BrNO4P
Molecular Weight
882.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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