Apoptosis inducer 30

• Target :

  Caspase|||Reactive Oxygen Species|||Apoptosis|||Cytochromes P450

• Related Pathways :

  Apoptosis|||NF-?B|||Metabolism|||Immunology/Inflammation|||Proteases/Proteasome

• Bioactivity :

  Apoptosisinducer 30 (Compound 15a) acts as an anticancer agent. It induces apoptosis in MCF-7 cells through the mitochondrial pathway. This compound elevates intracellular levels of reactive oxygen species (ROS), decreases mitochondrial membrane potential, and arrests the cell cycle at the G0/G1 phase. Apoptosisinducer 30 inhibits cell growth, with an IC50 value of 0.32 ?M against MCF-7 cells, and suppresses tumor growth in a mouse breast cancer model.

• Molecular Formula :

  C52H69BrNO4P

• Molecular Weight :

  882.99

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C