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STAT3/HDAC-IN-2

CAT: 0931-T200341-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200341-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
STAT, HDAC
Related Pathways
Chromatin/Epigenetic, JAK/STAT signaling, DNA Damage/DNA Repair, Stem Cells
Bioactivity
STAT3/HDAC-IN-2 (compound 18), a dual inhibitor of STAT3 and HDAC, promotes autophagy and apoptosis. This compound features an amphiphilic hydroxamic acid hybrid structure, derived from the natural product isopropanol lactone (IAL), and functions as a nanoscale anticancer agent. It has the ability to self-assemble into nanoparticles in aqueous environments, leading to enhanced tumor tissue accumulation, increased cellular uptake, and improved anticancer efficacy compared to its free state.
Molecular Formula
C28H32N2O7
Molecular Weight
508.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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