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JAK/HDAC-IN-2

CAT: 0013-GTR19230993-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230993-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK/HDAC-IN-2 is a dual-targeting 2-amino-4-phenylaminopyrimidine compound that potently inhibits JAK1/2 and HDAC3/6 at nanomolar levels. It induces apoptosis, blocks histone deacetylation and STAT3 phosphorylation, showing robust antiproliferative effects in studies of hematologic cancers and solid tumor models.
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C28H38N6O5S
Molecular Weight
570.7
Storage Conditions
-20°C
Notes
For research use only.

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