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PI3K/HDAC-IN-2

CAT: 0931-T62912-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62912-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2361418-65-5
Target
Others, PI3K, HDAC
Related Pathways
Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC50 values of 226 nM for PI3Kα, 279 nM for PI3Kβ, 467 nM for PI3Kγ, 29 nM for PI3Kδ, and 1.3 nM for HDAC1. PI3K/HDAC-IN-2 is selective for PI3Kδ and class I and IIb HDACs, exhibiting significant anticancer effects.
Smiles
O(CCN(C)C=1N=CC(C(NO)=O)=CN1)C=2C3=C(C=C(C2)C=4C=CC(OC)=NC4)C(C)=NC=N3
Molecular Formula
C23H23N7O4
Molecular Weight
461.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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