Apoptosis inducer 25

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Bioactivity :

  Apoptosisinducer 25 (Compound 4H) demonstrates potent anticancer capabilities by inhibiting the proliferation of BGC-823 cancer cells with an IC50 of 0.37 ?M. It induces apoptosis in BGC-823 cells, causes mitochondrial dysfunction, and arrests the cell cycle at the G2/M phase. Additionally, Apoptosisinducer 25 exhibits favorable pharmacokinetic properties in rats.

• Smiles :

  C(OCCCCOC(=O)C1=CC=C(O)C=C1)(=O)[C@]23[C@]([C@@]4([C@@](C)(CC2)[C@@]5(C)C(=CC4=O)[C@]6(C)[C@@](CC5)(C(C)(C)C(=O)C(C#N)=C6)[H])[H])(CC(C)(C)CC3)[H]

• Molecular Formula :

  C42H53NO7

• Molecular Weight :

  683.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2763063-15-4