Apoptosis inducer 25

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  Apoptosisinducer 25 (Compound 4H) demonstrates potent anticancer capabilities by inhibiting the proliferation of BGC-823 cancer cells with an IC50 of 0.37 ?M. It induces apoptosis in BGC-823 cells, causes mitochondrial dysfunction, and arrests the cell cycle at the G2/M phase. Additionally, Apoptosisinducer 25 exhibits favorable pharmacokinetic properties in rats.

• Smiles:

  C (OCCCCOC (=O) C1=CC=C (O) C=C1) (=O) [C@]23[C@] ([C@@]4 ([C@@] (C) (CC2) [C@@]5 (C) C (=CC4=O) [C@]6 (C) [C@@] (CC5) (C (C) (C) C (=O) C (C#N) =C6) [H]) [H]) (CC (C) (C) CC3) [H]

• Molecular Formula:

  C42H53NO7

• Molecular Weight:

  683.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2763063-15-4